NDLI: Comparison of BSGI and MRI as Approaches to Evaluating Residual Tumor Status after Neoadjuvant Chemotherapy in Chinese Women with Breast Cancer

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Comparison of BSGI and MRI as Approaches to Evaluating Residual Tumor Status after Neoadjuvant Chemotherapy in Chinese Women with Breast Cancer

Content Provider	MDPI
Author	Liu, Hongbiao Zhan, Hongwei Zhang, Ying He, Gangqiang Wang, Hui Zhang, Qiaoxia Zheng, Lili
Copyright Year	2021
Description	Background: The present retrospective study was designed to evaluate the relative diagnostic utility of breast-specific gamma imaging (BSGI) and breast magnetic resonance imaging (MRI) as means of evaluating female breast cancer patients in China. Methods: A total of 229 malignant breast cancer patients underwent ultrasound, mammography, BSGI, and MRI between January 2015 and December 2018 for initial tumor staging. Of these patients, 73 were subsequently treated via definitive breast surgery following neoadjuvant chemotherapy (NAC), of whom 17 exhibited a complete pathologic response (pCR) to NAC. Results: BSGI and MRI were associated with 76.8% (43/56) and 83.9% (47/56) sensitivity (BSGI vs. MRI, p = 0.341) values, respectively, as a means of detecting residual tumors following NAC, while both these approaches exhibited comparable specificity in this diagnostic context. The specificity of BSGI for detecting residual tumors following NAC was 70.6% (12/17), and that of MRI was 58.8% (10/17) (BSGI vs. MRI, p = 0.473). Conclusion: These results demonstrate that BSGI is a useful auxiliary approach to evaluating pCR to NAC treatment.
Starting Page	1846
e-ISSN	20754418
DOI	10.3390/diagnostics11101846
Journal	Diagnostics
Issue Number	10
Volume Number	11
Language	English
Publisher	MDPI
Publisher Date	2021-10-06
Access Restriction	Open
Subject Keyword	Diagnostics Oncology Womens Studies Breast-specific Gamma Imaging (bsgi) Neoadjuvant Chemotherapy (nac) Breast Cancer Magnetic Resonance Imaging (mri) Residual Tumor Size
Content Type	Text
Resource Type	Article

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