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Spray Freeze-Drying as a Solution to Continuous Manufacturing of Pharmaceutical Products in Bulk
| Content Provider | MDPI |
|---|---|
| Author | Adali, Merve B. Barresi, Antonello A. Boccardo, Gianluca Pisano, Roberto |
| Copyright Year | 2020 |
| Description | Pharmaceutical manufacturing is evolving from traditional batch processes to continuous ones. The new global competition focused on throughput and quality of drug products is certainly the driving force behind this transition which, thus, represents the new challenge of pharmaceutical manufacturing and hence of lyophilization as a downstream operation. In this direction, the present review deals with the most recent technologies, based on spray freeze-drying, that can achieve this objective. It provides a comprehensive overview of the physics behind this process and of the most recent equipment design. |
| Starting Page | 709 |
| e-ISSN | 22279717 |
| DOI | 10.3390/pr8060709 |
| Journal | Processes |
| Issue Number | 6 |
| Volume Number | 8 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2020-06-19 |
| Access Restriction | Open |
| Subject Keyword | Processes Pharmacology and Pharmacy Spray Freeze-drying Freezing Atomization Pharmaceuticals Continuous Manufacturing |
| Content Type | Text |
| Resource Type | Article |
