NDLI: SARS-CoV-2 mRNA Vaccine Breakthrough Infections in Fully Vaccinated Healthcare Personnel: A Systematic Review

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SARS-CoV-2 mRNA Vaccine Breakthrough Infections in Fully Vaccinated Healthcare Personnel: A Systematic Review

Content Provider	MDPI
Author	Ledda, Caterina Costantino, Claudio Motta, Giuseppe Cunsolo, Rosario Stracquadanio, Patrizia Liberti, Giuseppe Maltezou, Helena C. Rapisarda, Venerando
Copyright Year	2022
Description	The number of people vaccinated against COVID-19 increases worldwide every day; however, it is important to study the risk of breakthrough infections in vaccinated individuals at high risk of exposure such as healthcare personnel (HCP). A systematic literature review (SLR) applying the PRISMA declaration and the PECOS format using the following entry terms was used: “Health Personnel OR Healthcare Worker OR Healthcare Provider OR Healthcare Personnel AND breakthrough OR infection after vaccine*”. The research was carried out utilizing the following databases: SCOPUS, PubMed, Embase, and Web of Sciences. An overall very low incidence of post-vaccination breakthrough infections was found, ranging from 0.011 to 0.001 (per 100 individuals at risk). Our findings further support the published high effectiveness rates of mRNA vaccines in preventing SARS-CoV-2 infections among fully vaccinated HCP. Additional studies are needed to define the duration of the vaccine-induced protection among HCP.
Starting Page	9
e-ISSN	24146366
DOI	10.3390/tropicalmed7010009
Journal	Tropical medicine and infectious disease
Issue Number	1
Volume Number	7
Language	English
Publisher	MDPI
Publisher Date	2022-01-13
Access Restriction	Open
Subject Keyword	Tropical medicine and infectious disease Tropical Medicine and Infectious Disease Infectious Diseases Mrna-1273 Bnt162b2 Tak-919 Covid-19 Sars-cov-2 Post-vaccination Healthcare Personnel Pandemic Vaccination Asymptomatic Infection
Content Type	Text
Resource Type	Article

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