NDLI: Foot Revascularization Avoids Major Amputation in Persons with Diabetes and Ischaemic Foot Ulcers

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Foot Revascularization Avoids Major Amputation in Persons with Diabetes and Ischaemic Foot Ulcers

Content Provider	MDPI
Author	Meloni, Marco Morosetti, Daniele Giurato, Laura Stefanini, Matteo Loreni, Giorgio Doddi, Marco Panunzi, Andrea Bellia, Alfonso Gandini, Roberto Brocco, Enrico Lazaro-Martinez, José Luis Lauro, Davide Uccioli, Luigi
Copyright Year	2021
Description	The study aims to evaluate the effectiveness of foot revascularization in persons with diabetic foot ulcers (DFUs) and below-the-ankle (BTA) arterial disease. Consecutive patients referred for a new active ischaemic DFU requiring lower limb revascularization were considered. Among those, only patients with a BTA arterial disease were included. Revascularization procedures were retrospectively analysed: in the case of successful foot revascularization (recanalization of pedal artery, or plantar arteries or both) or not, patients were respectively divided in two groups, successful foot perfusion (SFP) and failed foot perfusion (FFP). Healing, minor and major amputation at 12 months of follow-up were evaluated and compared. Eighty patients (80) were included. The mean age was 70.5 ± 10.9 years, 55 (68.7%) were male, 72 (90%) were affected by type 2 diabetes with a mean duration of 22.7 ± 11.3 years. Overall 45 (56.2%) patients healed, 47 (58.7%) had minor amputation and 13 (16.2%) major amputation. Outcomes for SFP and FFP were respectively: healing (89.3 vs. 9.1%, p < 0.0001), minor amputation (44.7 vs. 78.8%, p = 0.0001), major amputation (2.1 vs. 36.3%, p < 0.0001). Failed foot revascularization resulted an independent predictor of non-healing, minor amputation, and major amputation. Foot revascularization is mandatory to achieve healing and avoid major amputation in persons with ischaemic DFU and BTA arterial disease.
Starting Page	3977
e-ISSN	20770383
DOI	10.3390/jcm10173977
Journal	Journal of clinical medicine
Issue Number	17
Volume Number	10
Language	English
Publisher	MDPI
Publisher Date	2021-09-02
Access Restriction	Open
Subject Keyword	Journal of clinical medicine Journal of Clinical Medicine Cardiology and Cardiovascular Diseases Diabetes Diabetic Foot Ulcer Critical Limb Ischaemia Revascularization Wound Healing
Content Type	Text
Resource Type	Article

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