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Effectiveness and Safety of COVID-19 Vaccine among Pregnant Women in Real-World Studies: A Systematic Review and Meta-Analysis
| Content Provider | MDPI |
|---|---|
| Author | Ma, Yirui Deng, Jie Liu, Qiao Du, Min Liu, Min Liu, Jue |
| Copyright Year | 2022 |
| Description | We aimed to assess the effectiveness and safety of coronavirus disease 2019 (COVID-19) vaccines for pregnant women in real-world studies. We searched for observational studies about the effectiveness and safety of COVID-19 vaccines among vaccinated pregnant women from inception to 6 November 2021. A total of 6 studies were included. We found that vaccination prevented pregnant women from SARS-CoV-2 infection (OR = 0.50, 95% CI, 0.35–0.79) and COVID-19-related hospitalization (OR = 0.50, 95% CI, 0.31–0.82). Messenger-RNA vaccines could reduce the risk of infection in pregnant women (OR = 0.13, 95% CI, 0.03–0.57). No adverse events of COVID-19 vaccination were found on pregnant, fetal, or neonatal outcomes. Our analysis confirmed the effectiveness and safety of COVID-19 vaccines for pregnant women. Policy makers should formulate targeted strategies to improve vaccine coverage in pregnant women. |
| Starting Page | 246 |
| e-ISSN | 2076393X |
| DOI | 10.3390/vaccines10020246 |
| Journal | Vaccines |
| Issue Number | 2 |
| Volume Number | 10 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2022-02-06 |
| Access Restriction | Open |
| Subject Keyword | Vaccines Womens Studies Covid-19 Vaccine Effectiveness Safety Pregnancy Systematic Review Meta-analysis |
| Content Type | Text |
| Resource Type | Article |
