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Optofluidic Particle Manipulation: Optical Trapping in a Thin-Membrane Microchannel
| Content Provider | MDPI |
|---|---|
| Author | Walker, Zachary J. Wells, Tanner Belliston, Ethan Walker, Seth B. Zeller, Carson Sampad, Mohammad Julker Neyen Saiduzzaman, S. M. Schmidt, Holger Hawkins, Aaron R. |
| Copyright Year | 2022 |
| Description | We demonstrate an optofluidic device which utilizes the optical scattering and gradient forces for particle trapping in microchannels featuring 300 nm thick membranes. On-chip waveguides are used to direct light into microfluidic trapping channels. Radiation pressure is used to push particles into a protrusion cavity, isolating the particles from liquid flow. Two different designs are presented: the first exclusively uses the optical scattering force for particle manipulation, and the second uses both scattering and gradient forces. Trapping performance is modeled for both cases. The first design, referred to as the orthogonal force design, is shown to have a 80% capture efficiency under typical operating conditions. The second design, referred to as the gradient force design, is shown to have 98% efficiency under the same conditions. |
| Starting Page | 690 |
| e-ISSN | 20796374 |
| DOI | 10.3390/bios12090690 |
| Journal | Biosensors |
| Issue Number | 9 |
| Volume Number | 12 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2022-08-27 |
| Access Restriction | Open |
| Subject Keyword | Biosensors Lab-on-a-chip Biosensor Nanopore Optofluidic Microfluidic Gradient Force Radiation Pressure Optical Trap |
| Content Type | Text |
| Resource Type | Article |
