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Efficacy and Safety of Auricular Acupuncture for the Treatment of Insomnia in Breast Cancer Survivors: A Randomized Controlled Trial
| Content Provider | MDPI |
|---|---|
| Author | Melanie, D. Höxtermann Sherko, Kümmel Buner, Katja Haller, Heidemarie Kohl, Wiebke Dobos, Gustav Reinisch, Mattea Cramer, Holger Voiss, Petra |
| Copyright Year | 2021 |
| Description | Among women, breast cancer is the most commonly diagnosed cancer worldwide. Sleep problems impair 40–70% of breast cancer survivors. This randomized controlled trial evaluates the effect of auricular acupuncture on sleep quality in breast cancer survivors suffering from insomnia. Fifty-two female breast cancer survivors with insomnia (mean age 55.73 ± 8.10 years) were randomized either to 10 treatments of auricular acupuncture within five weeks (n = 26), or to a single session of psychoeducation plus an insomnia advice booklet (n = 26). The primary outcome was sleep quality (measured by the Pittsburgh Sleep Quality Index) at week 5. Secondary outcomes were inflammation parameter (interleukin-6), stress, anxiety, depression, quality of life, and fatigue at week 5, and sleep quality, stress, anxiety, depression, quality of life, and fatigue 17 and 29 weeks after randomization. Intention-to-treat analysis showed a significantly stronger increase in sleep quality in the auricular acupuncture group compared to the psychoeducation group (p = 0.031; η^{2}$_{p}$ = 0.094) at week 5. Furthermore, auricular acupuncture improved stress (p = 0.030; η^{2}$_{p}$ = 0.094), anxiety (p = 0.001; η^{2}$_{p}$ = 0.192), and fatigue (p = 0.006; η^{2}$_{p}$ = 0.148) at week 5 compared to psychoeducation. No significant group difference was found concerning the other outcomes at week 5, or in any outcome at week 17 or week 29. No serious adverse events occurred during the study period. In conclusion, a semi-standardized group auricular acupuncture might be an effective and safe intervention in treating insomnia in breast cancer survivors in the short term, and may reduce stress, anxiety, and fatigue as well. Long-term effects remain questionable. |
| Starting Page | 4082 |
| e-ISSN | 20726694 |
| DOI | 10.3390/cancers13164082 |
| Journal | Cancers |
| Issue Number | 16 |
| Volume Number | 13 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-08-13 |
| Access Restriction | Open |
| Subject Keyword | Cancers Integrative and Complementary Medicine Breast Neoplasms Sleep Initiation and Maintenance Disorders Acupuncture Ear Cancer Survivors Randomized Controlled Trial Clinical Study Individualized Treatment |
| Content Type | Text |
| Resource Type | Article |
