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Axial and Nonaxial Migration of Red Blood Cells in a Microtube
Content Provider | MDPI |
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Author | Takeishi, Naoki Yamashita, Hiroshi Omori, Toshihiro Yokoyama, Naoto Sugihara-Seki, Masako |
Copyright Year | 2021 |
Description | Human red blood cells (RBCs) are subjected to high viscous shear stress, especially during microcirculation, resulting in stable deformed shapes such as parachute or slipper shape. Those unique deformed RBC shapes, accompanied with axial or nonaxial migration, cannot be fully described according to traditional knowledge about lateral movement of deformable spherical particles. Although several experimental and numerical studies have investigated RBC behavior in microchannels with similar diameters as RBCs, the detailed mechanical characteristics of RBC lateral movement—in particular, regarding the relationship between stable deformed shapes, equilibrium radial RBC position, and membrane load—has not yet been fully described. Thus, we numerically investigated the behavior of single RBCs with radii of 4 |
Starting Page | 1162 |
e-ISSN | 2072666X |
DOI | 10.3390/mi12101162 |
Journal | Micromachines |
Issue Number | 10 |
Volume Number | 12 |
Language | English |
Publisher | MDPI |
Publisher Date | 2021-09-28 |
Access Restriction | Open |
Subject Keyword | Micromachines Biophysics Red Blood Cells Axial Migration Lattice-boltzmann Method Finite Element Method Immersed Boundary Method Computational Biomechanics |
Content Type | Text |
Resource Type | Article |