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Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women
| Content Provider | MDPI |
|---|---|
| Author | Fabiola, Hernández-Rosas Erika, Orozco-Hernández Liliana, Maza-Sánchez Yasm, ín López-Vera Rey-Barrera, Manuel Conejo-Saucedo, Ulises Navarro-Vidal, Enrique Ascencio-Gordillo, María Del Carmen de León-Bautista, Mercedes Piedad |
| Copyright Year | 2021 |
| Description | Background. Globally, Sexually Transmitted Infections (STIs) are a major cause of morbidity in sexually active individuals, having complications in reproduction health and quality of life. In concordance with the Sustainable Development Goals (SDG), the study aimed to investigate the prevalence of Candida spp., Ureaplasma spp., Trichomonas vaginalis, Neisseria gonorrhoeae, Chlamydia trachomatis, HSV, and Mycoplasma spp. from cervicovaginal samples and to correlate them with the gynecological history of the patients. Methods. Our analytical, prospective, and cross-sectional study included 377 women who participated in a reproductive health campaign during 2015–2016. Anthropometric and gynecological variables were obtained. Cervicovaginal specimens were collected and analyzed with a multiplex in-house PCR to detect Candida spp., Ureaplasma spp., Trichomonas vaginalis, Neisseria gonorrhoeae, HSV, Mycoplasma spp., and Chlamydia trachomatis. Results. The positive cases were 175/377 (46.4%) to at least one of the microorganisms. The most frequent pathogen detected in this population was Ureaplasma spp. (n = 111, 29.4%), followed by Mycoplasma spp. (n = 56, 14.9%) and Candida spp. (n = 47, 12.5%); 33.7% of the positive cases were single infections, whereas 12.7% had coinfection. The multiplex PCR assay was designed targeting nucleotide sequences. Conclusions. Our data demonstrated that monitoring STIs among asymptomatic patients will encourage target programs to be more precisely and effectively implemented, as well as make these programs more affordable, to benefit society by decreasing the prevalence of STIs. |
| Starting Page | 1618 |
| e-ISSN | 20760817 |
| DOI | 10.3390/pathogens10121618 |
| Journal | Pathogens |
| Issue Number | 12 |
| Volume Number | 10 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-12-13 |
| Access Restriction | Open |
| Subject Keyword | Pathogens Womens Studies Sexually Transmitted Infection Pcr Multiplex Detection Sustainable Development Goals |
| Content Type | Text |
| Resource Type | Article |
