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Levels of Produced Antibodies after Vaccination with mRNA Vaccine; Effect of Previous Infection with SARS-CoV-2
| Content Provider | MDPI |
|---|---|
| Author | Konstantinidis, Theocharis Zisaki, Stavroula Mitroulis, Ioannis Konstantinidou, Eleni Kontekaki, Eftychia Romanidou, Gioulia Karvelas, Alexandros Nanousi, Ioanna Lazidis, Leonidas Cassimos, Dimitrios Tsigalou, Christina Martinis, Georges Panopoulou, Maria |
| Copyright Year | 2021 |
| Description | The aim of this study was to estimate the immunogenic effect of mRNA vaccine against SARS-CoV-2. This study included 510 participants who received mRNA vaccine. The measurement of anti-COVID-19 antibodies was performed using the Abbott SARS-CoV-2 IgG quantitative assay (Abbott). Overall, mean titer of anti-Spike antibodies was 19,319.2 ± 1787.5 AU/mL. Vaccination induced a robust immunogenic response in those previously infected with SARS-CoV-2 compared with non-infected subjects. Additionally, individuals that were asymptomatic after vaccination produced lower levels of antibodies compared to feverish individuals. In conclusion, remarkably high levels of anti-Spike COVID-19 antibodies were observed after vaccination. |
| Starting Page | 2842 |
| e-ISSN | 20770383 |
| DOI | 10.3390/jcm10132842 |
| Journal | Journal of clinical medicine |
| Issue Number | 13 |
| Volume Number | 10 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-06-27 |
| Access Restriction | Open |
| Subject Keyword | Journal of clinical medicine Journal of Clinical Medicine Infectious Diseases Vaccination Covid-19 Anti-sars-cov-2 Antibodies Sars-cov-2 |
| Content Type | Text |
| Resource Type | Article |