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Stability Performance Analysis of Various Packaging Materials and Coating Strategies for Chronic Neural Implants under Accelerated, Reactive Aging Tests
| Content Provider | MDPI |
|---|---|
| Author | Gong, Yan Liu, Wentai Wang, Runyu Brauer, Matthew Harris Zheng, Kristine Li, Wen |
| Copyright Year | 2020 |
| Description | Reliable packaging for implantable neural prosthetic devices in body fluids is a long-standing challenge for devices’ chronic applications. This work studied the stability of Parylene C (PA), SiO2, and Si3N4 packages and coating strategies on tungsten wires using accelerated, reactive aging tests in three solutions: pH 7.4 phosphate-buffered saline (PBS), PBS + 30 mM H2O2, and PBS + 150 mM H2O2. Different combinations of coating thicknesses and deposition methods were studied at various testing temperatures. Analysis of the preliminary data shows that the pinholes/defects, cracks, and interface delamination are the main attributes of metal erosion and degradation in reactive aging solutions. Failure at the interface of package and metal is the dominating factor in the wire samples with open tips. |
| Starting Page | 810 |
| e-ISSN | 2072666X |
| DOI | 10.3390/mi11090810 |
| Journal | Micromachines |
| Issue Number | 9 |
| Volume Number | 11 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2020-08-26 |
| Access Restriction | Open |
| Subject Keyword | Micromachines Coatings and Films Accelerated Reactive Aging Test Long Term Stability Packaging Implants Parylene C Sio2 Si3n4 |
| Content Type | Text |
| Resource Type | Article |
