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Cardiac Manifestations in Children with SARS-COV-2 Infection: 1-Year Pediatric Multicenter Experience
| Content Provider | MDPI |
|---|---|
| Author | Cantarutti, Nicoletta Battista, Virginia Adorisio, Rachele Cicenia, Marianna Campanello, Claudia Listo, Elisa Campana, Andrea Trocchio, Gianluca Drago, Fabrizio |
| Copyright Year | 2021 |
| Description | Since the spread of COVID-19, pediatric patients were initially considered less affected by SARS-COV-2, but current literature reported subsets of children with multisystem inflammatory syndrome (MIS-C). This study aims to describe the cardiac manifestation of SARS-COV-2 infection in a large cohort of children admitted to two Italian pediatric referral centers. Between March 2020 and March 2021, we performed a cardiac evaluation in 294 children (mean age 9 ± 5.9 years, male 60%) with active or previous SARS-COV-2 infection. Twenty-six showed ECG abnormalities: 63 repolarization anomalies, 13 Long QTc, five premature ventricular beats, two non-sustained ventricular tachycardia, and one atrial fibrillation. In total, 146 patients underwent cardiac biomarkers: NT-proBNP was elevated in 57, troponin in 34. An echocardiogram was performed in 98, showing 54 cardiac anomalies: 27 left-ventricular dysfunction, 42 pericarditis, 16 coronaritis. MIS-C was documented in 46 patients (mean age 9 ± 4.8 years, male 61%) with cardiac manifestations in 97.8%: 27 ventricular dysfunctions, 32 pericarditis, 15 coronaritis, 3 arrhythmias. All patients recovered, and during follow-up, no cardiac anomalies were recorded. Our experience showed that cardiac involvement is not rare in children with SARS-COV-2, and occurred in almost all patients with MIS-C. However, patients’ recovery is satisfactory and no additional events were reported during FU. |
| Starting Page | 717 |
| e-ISSN | 22279067 |
| DOI | 10.3390/children8080717 |
| Journal | Children |
| Issue Number | 8 |
| Volume Number | 8 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-08-23 |
| Access Restriction | Open |
| Subject Keyword | Children Pediatrics and Child Health Myocarditis Cardiac Involvement Mis-c Sars-cov-2 Covid-19 |
| Content Type | Text |
| Resource Type | Article |
