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Design, Synthesis, and Photophysical Properties of BODIPY-Labeled Lupane Triterpenoids
| Content Provider | MDPI |
|---|---|
| Author | Gubaidullin, Rinat Nedopekina, Darya Tukhbatullin, Adis Davletshin, Eldar Spivak, Anna |
| Copyright Year | 2020 |
| Description | Novel boron-dipyrromethene difluoride (4,4-difluoro-4-bora-3α,4α-diaza-s-indacene) (BODIPY)-lupane triterpenoid conjugates bearing a fluorescent marker at the C-2 position of ring A of the triterpene core were obtained via the Sonogashira reaction as a key step. The starting compounds in the cross-coupling reaction were C-2 propynyl derivatives of betulinic or betulonic acids and fluorescent dyes with an iodo-group at C-2 or meso position of BODIPY-platform. The newly elaborated coupling procedure might have applicability in the synthesis of fluorescently-labeled triterpenoid conjugates suitable for biological assays. |
| Starting Page | 11 |
| e-ISSN | 26734583 |
| DOI | 10.3390/ecsoc-24-08102 |
| Journal | Chemistry Proceedings |
| Issue Number | 1 |
| Volume Number | 3 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2020-11-13 |
| Access Restriction | Open |
| Subject Keyword | Chemistry Proceedings Organic Chemistry Pentacyclic Triterpenoids Betulinic Acid Bodipy Fluorescent Derivatives Sonogashira Coupling |
| Content Type | Text |