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Recent Advances and Challenges in Cancer Immunotherapy
| Content Provider | MDPI |
|---|---|
| Author | Peterson, Chelsea Denlinger, Nathan Yang, Yiping |
| Copyright Year | 2022 |
| Description | Cancer immunotherapy has revolutionized the field of oncology in recent years. Harnessing the immune system to treat cancer has led to a large growth in the number of novel immunotherapeutic strategies, including immune checkpoint inhibition, chimeric antigen receptor T-cell therapy and cancer vaccination. In this review, we will discuss the current landscape of immuno-oncology research, with a focus on elements that influence immunotherapeutic outcomes. We will also highlight recent advances in basic aspects of tumor immunology, in particular, the role of the immunosuppressive cells within the tumor microenvironment in regulating antitumor immunity. Lastly, we will discuss how the understanding of basic tumor immunology can lead to the development of new immunotherapeutic strategies. |
| Starting Page | 3972 |
| e-ISSN | 20726694 |
| DOI | 10.3390/cancers14163972 |
| Journal | Cancers |
| Issue Number | 16 |
| Volume Number | 14 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2022-08-17 |
| Access Restriction | Open |
| Subject Keyword | Cancers Immunotherapy Immune Checkpoint Inhibitor Chimeric Antigen Receptor (car)-t Cell Therapy Neoantigen Cancer Vaccine Tumor Microenvironment (tme) Tumor-associated Macrophages (tams) |
| Content Type | Text |
| Resource Type | Article |
