NDLI: Correlation Analysis between Intraocular Pressure and Extraocular Muscles Based on Orbital Magnetic Resonance T2 Mapping in Thyroid-Associated Ophthalmopathy Patients

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Correlation Analysis between Intraocular Pressure and Extraocular Muscles Based on Orbital Magnetic Resonance T2 Mapping in Thyroid-Associated Ophthalmopathy Patients

Content Provider	MDPI
Author	Luo, Ban Wang, Wei Li, Xinyu Zhang, Hong Zhang, Yaoli Hu, Weikun
Copyright Year	2022
Description	Background: The correlation between intraocular pressure (IOP) and the magnetic resonance imaging (MRI) parameters in thyroid-associated ophthalmopathy (TAO) patients was explored. Methods: This study included 82 eyes in 41 TAO patients who had a large difference in the IOP between each eye. We measured the T2 relaxation time (T2RT) of the extraocular muscles (EOMs), the orbital fat, and the area of the EOMs. Results: There was a positive correlation between IOP and exophthalmos, the clinical activity score (CAS), the T2RT (of the medial rectus (MR)), the area of the MR, inferior rectus (IR) and lateral rectus, and the mean area. We established a regression model with IOP as the dependent variable, and the area of the IR was statistically significant. Conclusions: High IOP in TAO patients was positively correlated with the degree of exophthalmos and EOM inflammation (especially the inferior rectus). The state of the EOMs in an orbital MRI may partially explain high IOP and provide the necessary clinical information for subsequent high IOP treatment.
Starting Page	3981
e-ISSN	20770383
DOI	10.3390/jcm11143981
Journal	Journal of clinical medicine
Issue Number	14
Volume Number	11
Language	English
Publisher	MDPI
Publisher Date	2022-07-08
Access Restriction	Open
Subject Keyword	Journal of clinical medicine Journal of Clinical Medicine Thyroid-associated Ophthalmopathy Extraocular Muscle Magnetic Resonance Imaging Intraocular Pressure T2 Relaxation Time
Content Type	Text
Resource Type	Article

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