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Fabrication of Microfluidic Devices for Emulsion Formation by Microstereolithography
| Content Provider | MDPI |
|---|---|
| Author | Max, Männel Baysak, Elif Thiele, Julian |
| Copyright Year | 2021 |
| Description | Droplet microfluidics—the art and science of forming droplets—has been revolutionary for high-throughput screening, directed evolution, single-cell sequencing, and material design. However, traditional fabrication techniques for microfluidic devices suffer from several disadvantages, including multistep processing, expensive facilities, and limited three-dimensional (3D) design flexibility. High-resolution additive manufacturing—and in particular, projection micro-stereolithography (PµSL)—provides a promising path for overcoming these drawbacks. Similar to polydimethylsiloxane-based microfluidics 20 years ago, 3D printing methods, such as PµSL, have provided a path toward a new era of microfluidic device design. PµSL greatly simplifies the device fabrication process, especially the access to truly 3D geometries, is cost-effective, and it enables multimaterial processing. In this review, we discuss both the basics and recent innovations in PµSL; the material basis with emphasis on custom-made photopolymer formulations; multimaterial 3D printing; and, 3D-printed microfluidic devices for emulsion formation as our focus application. Our goal is to support researchers in setting up their own PµSL system to fabricate tailor-made microfluidics. |
| Starting Page | 2817 |
| e-ISSN | 14203049 |
| DOI | 10.3390/molecules26092817 |
| Journal | Molecules |
| Issue Number | 9 |
| Volume Number | 26 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-05-10 |
| Access Restriction | Open |
| Subject Keyword | Molecules Projection Micro-stereolithography Microfluidics Droplets Emulsions Three-dimensional 3d Printing Additive Manufacturing |
| Content Type | Text |
| Resource Type | Article |
