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Improvement of PMMA Dental Matrix Performance by Addition of Titanium Dioxide Nanoparticles and Clay Nanotubes
| Content Provider | MDPI |
|---|---|
| Author | Cascione, Maria Francesca Matteis, Valeria De Pellegrino, Paolo Albanese, Giovanni Giorgi, Maria De Paladini, Fabio Corsalini, Massimo Rinaldi, Rosaria |
| Copyright Year | 2021 |
| Description | Over the last decades, several materials have been proposed for the fabrication of dental and mandibular prosthetic implants. Today, the poly(methyl-methacrylate) (PMMA) resin is the most spread material, due to its ease of processing, low cost, aesthetic properties, low weight, biocompatibility, and biostability in the oral cavity. However, the porous surface (which favors the adhesion of microorganisms) and the weak mechanical properties (which lead to wear or fracture) are the major concerns. The inclusion of engineered nanomaterials in the acrylic matrix could improve the performances of PMMA. In this study, we added two different kind of nanomaterials, namely titanium dioxide nanoparticles $(TiO_{2}$NPs) and halloysite clay nanotubes (HNTs) at two concentrations (1% and 3% w/w) in PMMA. Then, we assessed the effect of nanomaterials inclusion by the evaluation of specific physical parameters: Young’s modulus, roughness, and wettability. In addition, we investigated the potential beneficial effects regarding the Candida albicans (C. albicans) colonization reduction, the most common yeast responsible of several infections in oral cavity. Our experimental results showed an improvement of PMMA performance, following the addition of $TiO_{2}$NPs and HNTs, in a dose dependent manner. In particular, the presence of $TiO_{2}$NPs in the methacrylate matrix induced a greater increase in PMMA stiffness respect to HNTs addition. On the other hand, HNTs reduced the rate of C. albicans colonization more significantly than $TiO_{2}$NPs. The results obtained are of great interest for the improvement of PMMA physico-chemical properties, in view of its possible application in clinical dentistry. |
| Starting Page | 2027 |
| e-ISSN | 20794991 |
| DOI | 10.3390/nano11082027 |
| Journal | Nanomaterials |
| Issue Number | 8 |
| Volume Number | 11 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-08-09 |
| Access Restriction | Open |
| Subject Keyword | Nanomaterials Dentistry and Oral Surgery Tio2nps Hnts Poly(methyl Methacrylate) Oral Prostheses Mechanical Analysis Wettability Candida Albicans |
| Content Type | Text |
| Resource Type | Article |
