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COVID-19 Associated Invasive Pulmonary Aspergillosis: Diagnostic and Therapeutic Challenges
| Content Provider | MDPI |
|---|---|
| Author | Mohamed, Aia Rogers, Thomas R. Talento, Alida Fe |
| Copyright Year | 2020 |
| Description | Aspergillus co-infection in patients with severe coronavirus disease 2019 (COVID-19) pneumonia, leading to acute respiratory distress syndrome, has recently been reported. To date, 38 cases have been reported, with other cases most likely undiagnosed mainly due to a lack of clinical awareness and diagnostic screening. Importantly, there is currently no agreed case definition of COVID-19 associated invasive pulmonary aspergillosis (CAPA) that could aid in the early detection of this co-infection. Additionally, with the global emergence of triazole resistance, we emphasize the importance of antifungal susceptibility testing in order to ensure appropriate antifungal therapy. Herein is a review of 38 published CAPA cases, which highlights the diagnostic and therapeutic challenges posed by this novel fungal co-infection. |
| Starting Page | 115 |
| e-ISSN | 2309608X |
| DOI | 10.3390/jof6030115 |
| Journal | Journal of Fungi |
| Issue Number | 3 |
| Volume Number | 6 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2020-07-22 |
| Access Restriction | Open |
| Subject Keyword | Journal of Fungi Mycology Covid-19 Pneumonia Invasive Pulmonary Aspergillosis Diagnosis Multi-triazole Resistance Covid-19 Associated Invasive Pulmonary Aspergillosis |
| Content Type | Text |
| Resource Type | Article |
