NDLI: Effectiveness of Clinical Pharmacist Service on Drug-Related Problems and Patient Outcomes for Hospitalized Patients with Chronic Kidney Disease: A Randomized Controlled Trial

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Effectiveness of Clinical Pharmacist Service on Drug-Related Problems and Patient Outcomes for Hospitalized Patients with Chronic Kidney Disease: A Randomized Controlled Trial

Content Provider	MDPI
Author	Song, Yun-Kyoung Jeong, Sohyun Han, Nayoung Na, Heejin Jang, Ha Sohn, Minji Kim, Yon Joo, Kwon-Wook Oh, Kook-Hwan Kim, Dong Lee, Hajeong Oh, Jung
Copyright Year	2021
Description	(1) Background: The study aimed to analyze the effectiveness of clinical pharmacist services on drug-related problems (DRPs) and patient outcomes in inpatients with chronic kidney disease (CKD). (2) Methods: In a randomized controlled trial, the participants in the intervention group received pharmacist services, including medication reconciliation, medication evaluation and management, and discharge pharmaceutical care transition services. Participants in the control group received usual care. The primary outcome was the number of DRPs per patient at discharge. (3) Results: The baseline characteristics of 100 participants included the following: mean age, 52.5 years; median eGFR, 9.2 mL/min/1.73 m2. The number of DRPs in the intervention group during hospitalization increased significantly with decreasing eGFR (PR, 0.970; 95% CI, 0.951–0.989) and an increasing number of unintentional medication discrepancies at admission (PR, 1.294; 95% CI, 1.034–1.620). At discharge, the number of DRPs per patient was 0.94 ± 1.03 and 1.96 ± 1.25 in the intervention and control groups, respectively (p < 0.001). The service had a significant effect on the reduction of the unintentional discrepancies at discharge (p < 0.001). (4) Conclusion: Hospital pharmacists play an important role in the prevention of DRPs at discharge and unintentional medication discrepancies in inpatients with CKD.
Starting Page	1788
e-ISSN	20770383
DOI	10.3390/jcm10081788
Journal	Journal of clinical medicine
Issue Number	8
Volume Number	10
Language	English
Publisher	MDPI
Publisher Date	2021-04-20
Access Restriction	Open
Subject Keyword	Journal of clinical medicine Journal of Clinical Medicine Integrative and Complementary Medicine Pharmaceutical Care Service Chronic Kidney Disease Hospitalized Patients Drug-related Problems
Content Type	Text
Resource Type	Article

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