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Assessing the Prognosis of Patients with Myelodysplastic Syndromes (MDS)
| Content Provider | MDPI |
|---|---|
| Author | Kasprzak, Annika Nachtkamp, Kathrin Gattermann, Norbert Germing, Ulrich |
| Copyright Year | 2022 |
| Description | Prognostic stratification in patients with myelodysplastic syndrome (MDS) relies on a number of key factors. Combining such patient-related and disease-related prognostic parameters into useful assessment tools remains a challenge. The most widely used scoring systems include the international prognostic scoring system (IPSS), the revised IPSS (IPSS-R), the World Health Organization (WHO) Prognostic Scoring System (WPSS), and the new molecular IPSS (IPSS-M). Similar to the IPSS-R and the IPSS-M, the chronic myelomonocytic leukemia (CMML) prognostic scoring system (CPSS) and the CPSS molecular (CPSS-mol) are powerful and reliable prognostic tools that help to assess the individual prognosis of patients with CMML. The well-established prognostic assessment of MDS and CMML may be further augmented by additional disease-related parameters, such as somatic mutations, or patient-related factors, such as comorbidities. In this article, we briefly describe useful prognostic scoring systems for myelodysplastic syndromes and identify some open questions that require further investigation. |
| Starting Page | 1941 |
| e-ISSN | 20726694 |
| DOI | 10.3390/cancers14081941 |
| Journal | Cancers |
| Issue Number | 8 |
| Volume Number | 14 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2022-04-12 |
| Access Restriction | Open |
| Subject Keyword | Cancers Hematology Myelodysplastic Syndromes Prognosis Chronic Myelomonocytic Leukemia |
| Content Type | Text |
| Resource Type | Article |
