NDLI: The Prevention of Periprosthetic Joint Infection in Primary Total Hip Arthroplasty Using Pre-Operative Chlorhexidine Bathing

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The Prevention of Periprosthetic Joint Infection in Primary Total Hip Arthroplasty Using Pre-Operative Chlorhexidine Bathing

Content Provider	MDPI
Author	Su, Wen-Chi Lai, Yu-Chin Lee, Cheng-Hung Shih, Cheng-Min Chen, Chao-Ping Hung, Li-Ling Wang, Shun-Ping
Copyright Year	2021
Description	Periprosthetic joint infection (PJI) after total hip arthroplasty (THA) is a devastating complication. The aim of this study was to investigate whether preoperative bathing using chlorhexidine gluconate (CHG) before THA can effectively reduce the postoperative PJI rate. A total of 933 primary THA patients, with the majority being female (54.4%) were included in the study. Primary THA patients who performed preoperative chlorhexidine bathing were assigned to the CHG group (190 subjects), and those who did not have preoperative chlorhexidine bathing were in the control group (743 subjects). The effects of chlorhexidine bathing on the prevention of PJI incidence rates were investigated. Differences in age, sex, and the operated side between the two groups were not statistically significant. Postoperative PJI occurred in four subjects, indicating an infection rate of 0.43% (4/933). All four infected subjects belonged to the control group. Although the PJI cases were significantly more in the control group than in the CHG group, statistical analysis revealed no statistical significance in the risk of PJI occurrence between the two groups (p = 0.588). Preoperative skin preparation by bathing with a 2% chlorhexidine gluconate cleanser did not produce significant effects on the prevention of postoperative PJI in primary THA.
Starting Page	434
e-ISSN	20770383
DOI	10.3390/jcm10030434
Journal	Journal of clinical medicine
Issue Number	3
Volume Number	10
Language	English
Publisher	MDPI
Publisher Date	2021-01-23
Access Restriction	Open
Subject Keyword	Journal of clinical medicine Journal of Clinical Medicine Orthopedics Surgical Site Infection Chlorhexidine Bathing Total Hip Arthroplasty Primary Tha Periprosthetic Joint Infection Pji
Content Type	Text
Resource Type	Article

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