Loading...
Please wait, while we are loading the content...
Similar Documents
Micronutrient Deficiencies in Patients with Decompensated Liver Cirrhosis
| Content Provider | MDPI |
|---|---|
| Author | Cristina, Solé Valent, í Puig-Diví Gemma, Solé Jordi, Sánchez-Delgado Llibre-Nieto, Gemma Lira, Alba Vergara, Mercedes Casas, Meritxell Humanes, Antonia Grau, Laia Barradas, Josep Miquel, Mireia |
| Copyright Year | 2021 |
| Description | Patients with cirrhosis often develop malnutrition and micronutrient deficiencies, leading to a worse prognosis and increased mortality. Our main goal was to assess the prevalence of micronutrient deficiencies in patients with decompensated cirrhosis. This was a prospective single-center study including 125 consecutive patients hospitalized for acute decompensation of cirrhosis (mostly of alcoholic etiology). A blood test including trace elements and vitamins was performed on admission. The main micronutrient deficiencies observed were vitamin D (in 94.5%), vitamin A (93.5%), vitamin B6 (60.8%) and zinc (85.6%). Patients in Child-Pugh class C had lower levels of vitamin A (p < 0.0001), vitamin E (p = 0.01) and zinc (p < 0.001), and higher levels of ferritin (p = 0.002) and vitamin B12 (p < 0.001) than those in Child-Pugh class A and B. Patients with a higher model of end-stage liver disease (MELD) score had lower levels of vitamin A (p < 0.0001), vitamin E (p < 0.001), magnesium (p = 0.01) and zinc (p = 0.001), and higher levels of ferritin (p = 0.002) and vitamin B12 (p < 0.0001). Severe hepatic insufficiency correlated with lower levels of zinc, vitamin E and vitamin A, and higher levels of vitamin B12 and ferritin. |
| Starting Page | 1249 |
| e-ISSN | 20726643 |
| DOI | 10.3390/nu13041249 |
| Journal | Nutrients |
| Issue Number | 4 |
| Volume Number | 13 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-04-10 |
| Access Restriction | Open |
| Subject Keyword | Nutrients Gastroenterology and Hepatology Micronutrient Deficiency Trace Element Deficiency Vitamin Deficiency Malnutrition Decompensated Cirrhosis. |
| Content Type | Text |
| Resource Type | Article |
