NDLI: Exploring Various Techniques for the Chemical and Biological Synthesis of Polymeric Nanoparticles

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Exploring Various Techniques for the Chemical and Biological Synthesis of Polymeric Nanoparticles

Content Provider	MDPI
Author	Pulingam, Thiruchelvi Foroozandeh, Parisa Chuah, Jo-Ann Sudesh, Kumar
Copyright Year	2022
Description	Nanoparticles (NPs) have remarkable properties for delivering therapeutic drugs to the body’s targeted cells. NPs have shown to be significantly more efficient as drug delivery carriers than micron-sized particles, which are quickly eliminated by the immune system. Biopolymer-based polymeric nanoparticles (PNPs) are colloidal systems composed of either natural or synthetic polymers and can be synthesized by the direct polymerization of monomers (e.g., emulsion polymerization, surfactant-free emulsion polymerization, mini-emulsion polymerization, micro-emulsion polymerization, and microbial polymerization) or by the dispersion of preformed polymers (e.g., nanoprecipitation, emulsification solvent evaporation, emulsification solvent diffusion, and salting-out). The desired characteristics of NPs and their target applications are determining factors in the choice of method used for their production. This review article aims to shed light on the different methods employed for the production of PNPs and to discuss the effect of experimental parameters on the physicochemical properties of PNPs. Thus, this review highlights specific properties of PNPs that can be tailored to be employed as drug carriers, especially in hospitals for point-of-care diagnostics for targeted therapies.
Starting Page	576
e-ISSN	20794991
DOI	10.3390/nano12030576
Journal	Nanomaterials
Issue Number	3
Volume Number	12
Language	English
Publisher	MDPI
Publisher Date	2022-02-08
Access Restriction	Open
Subject Keyword	Nanomaterials Pharmacology and Pharmacy Polymeric Nanoparticles Nanoprecipitation Emulsification Solvent Evaporation Emulsification Solvent Diffusion Polyhydroxyalkanoates (pha) Natural Nanoparticles
Content Type	Text
Resource Type	Article

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