NDLI: The Clinical Significance of Asymptomatic Gross and Microscopic Hematuria in Children

Content Provider	JAMA Network
Author	Bergstein, Jerry Leiser, Jeffrey Andreoli, Sharon
Copyright Year	2005
Abstract	Background: The development of asymptomatic gross or microscopic hematuria is relatively common in children. Objective: To evaluate the clinical importance of hematuria in children and the necessity for such an evaluation using a defined diagnostic protocol. Design: The protocol included a personal and family history, physical examination and blood pressure determination, and a set of comprehensive laboratory and radiological examinations. Results: Of 342 children with microscopic hematuria, no cause was uncovered in 274 patients. The most common cause discovered was hypercalciuria (16%), followed by post–streptococcal glomerulonephritis (1%). Of 228 children with gross hematuria, no cause was uncovered in 86 patients. The most common cause discovered was hypercalciuria (22%). Ten patients had clinically important structural abnormalities. Fifty-three patients qualified for renal biopsy; 36 had Ig: A nephropathy. Conclusions: Our results suggest that diagnostic evaluation for potential causes of asymptomatic microscopic hematuria in children may not be necessary. Because microscopic hematuria can, rarely, be the first sign of occult renal disease, Along-term follow-up is mandatory. As clinically important abnormalities of the urinary tract are commonly discovered in children with asymptomatic gross hematuria, a thorough diagnostic evaluation is warranted.
Ending Page	355
Starting Page	353
Page Count	3
File Format	PDF HTM / HTML
ISSN	10724710
DOI	10.1001/archpedi.159.4.353
Issue Number	4
Journal	Archives of Pediatrics & Adolescent Medicine
Volume Number	159
Language	English
Publisher	American Medical Association
Publisher Date	2005-04-01
Access Restriction	Open
Subject Keyword	microscopic hematuria hematuria hypercalciuria renal biopsy gross hematuria iga glomerulonephritis post-streptococcal glomerulonephritis follow-up kidney diseases
Content Type	Text
Resource Type	Article
Subject	Pediatrics, Perinatology and Child Health

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