NDLI: Isolated Brain Metastasis of Malignant Choroidal Melanoma 27 Years After Enucleation

Content Provider	JAMA Network
Author	Midena, Edoardo Belvis, Valentina de Tos, Angelo P. Dei Antonini, Cristina
Copyright Year	1999
Abstract	Choroidal melanoma primarily metastasizes to the liver. Isolated extrahepatic metastases have rarely been reported and they generally resulted in death within 6 months. We describe a patient who developed an isolated brain metastasis 27 years after his left eye was enucleated for choroidal melanoma. The metastasis was successfully treated with surgery and radiotherapy. The patient is alive and disease free 3 years after treatment of the metastasis. Posterior location and other clinical and morphologic characteristics of primary choroidal melanoma could explain the unusually long latency of this solitary extrahepatic metastatic disease. Lifelong surveillance to detect early signs of metastasis is mandatory for any patient treated for choroidal melanoma.
Ending Page	1556
Starting Page	1553
Page Count	4
File Format	PDF HTM / HTML
ISSN	00039950
DOI	10.1001/archopht.117.11.1553
Issue Number	11 (Theme: New Technology)
Journal	Archives of Ophthalmology
Volume Number	117
Language	English
Publisher	American Medical Association
Publisher Date	1999-11-01
Access Restriction	Open
Subject Keyword	metastatic malignant neoplasm to brain cellular enucleation enucleation procedure malignant melanoma of choroid neoplasm metastasis operative surgical procedures radiation therapy
Content Type	Text
Resource Type	Report
Subject	Ophthalmology

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Isolated Brain Metastasis of Malignant Choroidal Melanoma 27 Years After Enucleation