NDLI: EFFECTS OF INTRAVENOUS ADMINISTRATION OF HYPERTONIC SOLUTIONS OF DEXTROSE: WITH SPECIAL REFERENCE TO THE CEREBROSPINAL FLUID PRESSURE

Content Provider	JAMA Network
Author	MASSERMAN, JULES H.
Copyright Year	1934
Abstract	Following the discovery that the introduction of concentrated solutions of various salts or of dextrose into the blood stream1or the gastro-intestinal tract2of an experimental animal causes a diminution in its cerebrospinal fluid pressure, hypertonic solutions have been administered clinically by different routes in attempts to reduce intracranial hypertension in patients suffering from brain trauma,3brain tumor,4meningitis5or brain edema with acute infections.6However, more recent observations both in animals7and in a small number of human beings8have indicated that the initial decrease in the tension of the cerebrospinal fluid induced by these methods is superseded within from one to three hours by a persistent rise in subarachnoid pressure and an exacerbation of the initial symptoms of intracranial hypertension. The problem, therefore, appeared to require further investigation. It is my purpose in this paper to report a study of
Ending Page	2086
Starting Page	2084
Page Count	3
File Format	PDF HTM / HTML
ISSN	00029955
DOI	10.1001/jama.1934.02750250010006
Issue Number	25
Journal	Journal of the American Medical Association
Volume Number	102
Language	English
Publisher	American Medical Association
Publisher Date	1934-06-23
Access Restriction	Subscribed
Content Type	Text
Resource Type	Article
Subject	Medicine

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EFFECTS OF INTRAVENOUS ADMINISTRATION OF HYPERTONIC SOLUTIONS OF DEXTROSE: WITH SPECIAL REFERENCE TO THE CEREBROSPINAL FLUID PRESSURE