Metal-organic framework based highly selective fluorescence turn-on probe for hydrogen sulphide

Content Provider	IISER Pune
Author	Saha, Tanmoy Desai, Aamod V. Talukdar, Pinaki Nagarkar, Sanjog S. Ghosh, Sujit K.
Abstract	Hydrogen sulphide ($H_2S$) is known to play a vital role in human physiology and pathology which stimulated interest in understanding complex behaviour of $H_2S$ Discerning the pathways of $H_2S$ production and itsmode of action is still a challenge owing to its volatile and reactive nature. Herein we report azide functionalized metal-organic framework (MOF) as a selective turn-on fluorescent probe for $H_2S$ detection.The MOF shows highly selective and fast response towards $H_2S$ even in presence of other relevant biomolecules. Low cytotoxicity and $H_2S$ detectionin live cells, demonstrate the potential of MOF towards monitoring $H_2S$ chemistry in biological system. To the best of our knowledge this is the first example of MOF that exhibit fast and highly selective fluorescence turn-on response towards $H_2S$ under physiological conditions.
ISSN	20452322
Journal	Scientific Reports
Volume Number	4
Alternate Webpage(s)	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/1989
Language	English
Publisher	Nature Research
Publisher Date	2014-11-14
Publisher Department	Dept. of Chemistry
Access Restriction	Open
Subject Keyword	Metal-Organic Framework
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary