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Selective Para Metalation Of Unprotected 3-methoxy And 3,5-dimethoxy Benzoic Acids With N-butyl Lithium-potassium Tert-butoxide (LIC-KOR): Synthesis Of 3,5-dimethoxy-4-methyl Benzoic Acid
| Content Provider | Indian Institute of Science (IISc) |
|---|---|
| Author | Sinha, Surajit Mandal, Bhubaneswar Chandrasekaran, Srinivasan |
| Copyright Year | 2000 |
| Abstract | The potassium salt of 3-methoxy and 3,5-dimethoxy benzoic acids undergoes deprotonation at the position para to the carboxylate group selectively when treated with LIC-KOR in THF at -78 degrees C and it has been extended to the synthesis of 3,5-dimethoxy-4-methyl benzoic acid. (C) 2000 Elsevier Science Ltd. All rights reserved. |
| File Format | |
| Journal | PeerReviewed |
| Language | English |
| Publisher | Elsevier science |
| Publisher Date | 2000-04-22 |
| Access Restriction | Authorized |
| Subject Keyword | Organic Chemistry |
| Content Type | Text |
| Resource Type | Article |