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| Content Provider | IET Digital Library |
|---|---|
| Author | Bian, Chunhui Lin, Huiming Li, Xiaofeng Ma, Jie Jiang, Pingping Qu, Fengyu |
| Abstract | Spherical macroporous poly(lactic-co-glycolic acid) (PLGA) has been synthesised using an emulsion method. Polyvinyl alcohol and Pluronic F127 have been used as dispersing and porogen agent, respectively. The diameter of the spherical PLGA is about 20 μm and the pore size of the PLGA macroporous is about 2–2.5 μm observed by scanning electron microscopy. After immersing in simulated body fluid, the PLGA materials can induce the formation of hydroxyapatite (HAP) on their surface. The HAP-PLGA has been obtained and used as the host for drug release. Furthermore, the drug-loaded samples possess the various drug release performance by adjusting the thickness of the HAP layer. This highly satisfied composite material is expected to be promising in the applications in tissue regeneration engineering. |
| Starting Page | 1 |
| Ending Page | 4 |
| Page Count | 4 |
| ISSN | 17518741 |
| Volume Number | 9 |
| e-ISSN | 1751875X |
| Issue Number | Issue 1, Feb (2015) |
| Alternate Webpage(s) | https://digital-library.theiet.org/content/journals/iet-nbt/9/1 |
| Alternate Webpage(s) | https://digital-library.theiet.org/content/journals/10.1049/iet-nbt.2013.0066 |
| Journal | IET Nanobiotechnology |
| Publisher Date | 2014-06-03 |
| Access Restriction | Open |
| Rights Holder | © The Institution of Engineering and Technology |
| Subject Keyword | Bioceramics Biomedical Material Bone Bone Tissue Regeneration Ca10PO46(OH)2 Calcium Compounds Composite Material Drug Delivery System Drug Release Elastomers Emulsion Method Emulsions HAP-PLGA Hydroxyapatite Material Preparation Patient Care And Treatment Plastics Pluronic F127 Porogen Agent Polymer Blends Polyvinyl Alcohol Dispersing Agent Porous Material Preparation of Polymers And Plastics Scanning Electron Microscopy Simulated Body Fluid Spherical Macroporous Poly(lactic-co-glycolic Acid) Structure of Polymers Structure of Powder Tissue Engineering Tissue Regeneration Engineering |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Electronic, Optical and Magnetic Materials Electrical and Electronic Engineering Biotechnology |
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