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| Content Provider | IET Digital Library |
|---|---|
| Author | Ke, Peng Sun, Honghao Liu, Mingxing Su, Zhengding Hu, Kanghong Zhua, Hongda Guo, Huilin Sun, Hongmei Andresen, Thomas Lars Olsen, Lars Folke |
| Abstract | A synthetic peptide octaarginine which mimics human immunodeficiency virus-1, Tat protein is used as cell penetrating moiety for new pH nanosensors which demonstrate enhanced cellular uptake and expanded measurement range from pH 3.9 to pH 7.3 by simultaneously incorporating two complemental pH-sensitive fluorophores in a same nanoparticle. The authors believe that this triple fluorescent pH sensor provides a new tool to pH measurements that can have application in cellular uptake mechanism study and new nanomedicine design. |
| Starting Page | 8 |
| Ending Page | 12 |
| Page Count | 5 |
| ISSN | 17518741 |
| Volume Number | 10 |
| e-ISSN | 1751875X |
| Issue Number | Issue 1, Feb (2016) |
| Alternate Webpage(s) | https://digital-library.theiet.org/content/journals/iet-nbt/10/1 |
| Alternate Webpage(s) | https://digital-library.theiet.org/content/journals/10.1049/iet-nbt.2014.0070 |
| Journal | IET Nanobiotechnology |
| Publisher Date | 2016-02-01 |
| Access Restriction | Open |
| Rights Holder | © The Institution of Engineering and Technology |
| Subject Keyword | Biochemistry Biological Transport Biomedical Engineering Biomedical Imaging/measurement Biomedical Measurement Biomembrane Transport Biomimetics Biomolecular Dynamics Biosensor Cell Penetrating Moiety Cell Penetrating Peptide Cellular And Subcellular Transmembrane Physics Cellular Uptake Mechanism Study Chemical Sensor Chemical Variables Measurement Complemental PH-sensitive Fluorophore Incorporation Dyes Electromagnetic Radiation Spectrometry (chemical Analysis) Extended Measurement Range Fabrication of MEMS And NEMS Device Human Immunodeficiency Virus-1 Tat Protein Mimicking Interactions with Radiations at The Biomolecular Level Micromechanical And Nanomechanical Device And System Microorganisms Microsensors And Nanosensors Molecular Biophysics Molecular Configurations Molecular Pattern Recognition Molecular Probes Nanocomposite Nanofabrication Nanomedicine Nanomedicine Design Nanoparticle Nanosensor Nanotechnology Application in Biomedicine Natural And Artificial Biomembranes Octaarginine Optical And Laser Radiation Optical Sonsor PH Measurement Physical Chemistry of Biomolecular Solutions And Condensed State Physics of Subcellular Structure Polymer Polymeric PH Nanosensor Proteins Spectrochemical Analysis Synthetic Peptide Triple Fluorescent PH Sensor |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Electronic, Optical and Magnetic Materials Electrical and Electronic Engineering Biotechnology |
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