NDLI: Synthesis, characterisation and potential biomedical applications of magnetic core–shell structures: carbon-, dextran-, SiO2- and ZnO-coated Fe3O4 nanoparticles

Content Provider	IET Digital Library
Author	Boustani, Komail Shayesteh, Saber Farjami Salouti, Mojtaba Jafari, Atefeh Shal, Alireza Ahadpour
Abstract	Due to the strong effect of nanoparticles' size and surface properties on cellular uptake and bio-distribution, the selection of coating material for magnetic core–shell nanoparticles (CSNPs) is very important. In this study, the effects of four different biocompatible coating materials on the physical properties of Fe3O4 (magnetite) nanoparticles (NPs) for different biomedical applications are investigated and compared. In this regard, magnetite NPs are prepared by a simple co-precipitation method. Then, CSNPs including Fe3O4 as a core and carbon, dextran, ZnO (zincite) and SiO2 (silica) as different shells are synthesised using simple one- or two-step methods. A comprehensive study is carried out on the prepared samples using X-ray diffraction, vibrating sample magnetometry, transmission electron microscopy and Fourier transform infrared spectroscopy analyses. According to the authors' findings, it is suggested that carbon- and dextran-coated magnetite NPs with high M s have great potential in the application of magnetic resonance imaging contrast agents. Moreover, silica-coated magnetite NPs with high coercivity are potentially suitable candidates for hyperthermia and ZnO-coated Fe3O4 is potentially suitable for photothermal therapy.
Starting Page	78
Ending Page	86
Page Count	9
ISSN	17518741
Volume Number	12
e-ISSN	1751875X
Issue Number	Issue 1, Feb (2018)
Alternate Webpage(s)	https://digital-library.theiet.org/content/journals/iet-nbt/12/1
Alternate Webpage(s)	https://digital-library.theiet.org/content/journals/10.1049/iet-nbt.2017.0044
Journal	IET Nanobiotechnology
Publisher Date	2017-11-01
Access Restriction	Open
Rights Holder	© The Institution of Engineering and Technology
Subject Keyword	Biocompatible Coating Materials Biodistribution Biomedical Application Biomedical Material Biomedical MRI Carbon Cellular Uptake Co-precipitation Coating Material Coatings CSNP Dextran Fine-particle Magnetic System Fourier Transform Infrared Spectroscopy Fourier Transform Spectra Hyperthermia Infrared And Raman Spectra And Scattering (Condensed Matter) Infrared Spectra Inorganic SemiConductor And Insulator Iron Compound Magnetic Core-shell NanoParticle Magnetic Particle Magnetic Resonance Imaging Contrast Agent Magnetometry Method of Nanofabrication And Processing Nanofabrication Nanomedicine Nanoparticle Nanotechnology Application in Biomedicine Nanotube And Nanostructured Material Optical Property Photothermal Therapy Radiation Therapy Silica Silicon Compound SiO2-Fe3O4 Structure of Solid Clusters Transmission Electron Microscopy Vibrating Sample Magnetometer X-Ray Diffraction Zinc Compound Zincite ZnO-Fe3O4
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology Electronic, Optical and Magnetic Materials Electrical and Electronic Engineering Biotechnology

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