NDLI: Antibacterial AgNPs/CaP biocomposites

Content Provider	IEEE Xplore Digital Library
Author	Ivanova, A.A. Surmenev, R.A. Surmeneva, M.A. Mukhametkaliyev, T. Sharonova, A.A. Grubova, I.Yu. Loza, K. Chernousova, S. Prymak, O. Epple, M.
Copyright Year	2014
Description	Author affiliation: Dept. of Theor. & Exp. Phys. Centre of Technol., Nat. Res. Tomsk Polytech. Univ., Tomsk, Russia (Ivanova, A.A.; Surmenev, R.A.; Surmeneva, M.A.; Mukhametkaliyev, T.; Sharonova, A.A.; Grubova, I.Yu.) \|\| Inorg. Chem. & Center for Nanointegration Duisburg-Essen (CeNIDE), Univ. of Duisburg-Essen, Essen, Germany (Loza, K.; Chernousova, S.; Prymak, O.; Epple, M.)
Abstract	The modification of implant surface is in the focus of many scientists worldwide. In this study, multifunctional biocomposite on the basis of calcium phosphate coating and silver nanoparticles has been fabricated through the use of nanofabrication techniques. Dense nanocrystalline HA film was deposited over AgNPs. The properties as well as the in vitro behavior of the developed biocomposites have been studied. The diffraction patterns of the biocomposites revealed the peaks of crystalline HA and silver (Ag). The release of Ag from the developed biocomposites was evaluated. The concentration of the released silver ions for 7 days of dissolution was 0.27±0.02 μg/mL and 0.54±0.02 μg/mL for phosphate and acetate buffers, respectively. In order to estimate the cytotoxicity of the samples the functional activity of osteoclasts, in particular, cell morphology, multinuclearity, actin ring and resorption pit on the substrates coated with HA and AgNPs-HA have been evaluated.
Starting Page	472
Ending Page	474
File Size	1329201
Page Count	3
File Format	PDF
e-ISBN	9781479960620
DOI	10.1109/IFOST.2014.6991166
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2014-10-21
Publisher Place	Bangladesh
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	RF magnetron sputtering Silver hydroxyapatite multilayer structures silver nanoparticles Surface morphology Implants Antibacterial activity Coatings Surface treatment Substrates thin films
Content Type	Text
Resource Type	Article

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