NDLI: Single-walled carbon-nanotube forest immunosensor for amplified detection of cancer biomarkers

Content Provider	IEEE Xplore Digital Library
Author	Gong, J.D. Jensen, G. Bhirde, A. Xin Yu Munge, B. Patel, V. Sang Nyon Kim Silvio Gutkind, J. Papadimitrakopoulos, F. Rusling, J.F.
Copyright Year	2006
Description	Author affiliation: Dept. of Chem., Connecticut Univ., Storrs, CT (Gong, J.D.; Jensen, G.; Bhirde, A.; Xin Yu; Munge, B.)
Abstract	Prostate specific antigen (PSA) is a major biomarker used clinically in the detection of prostate cancer. Current commercial immunoassays for detection of this biomarker rely on spectroscopic absorbance and electro-chemiluminescence which are able to detect as low as 0.03 ng/mL of PSA within 100muL of serum. In this paper, a novel amplified electrochemical technique for detection of prostate specific antigen is described. This electrochemical approach is a highly sensitive method that can have detection limit of 0.004 ng/mL in only 10 mL of serum, a mass detection limit 75 times lower than current commercial techniques. This highly sensitive, low cost and fast detection method not only allows for detection of cancer biomarkers in serum, but also in tissue and cells. Moreover, immunoassay arrays based on this methodology will be highly promising for application in large-scale clinical screening and point-of-care diagnostics. Characterization of the anti-PSA amplification tag in this amplification system using TEM, AFM, SEM, and CE is also described
Starting Page	5
Ending Page	207
File Size	318186
Page Count	203
File Format	PDF
ISBN	0769525474
DOI	10.1109/BSN.2006.50
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-04-03
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Proteins Scanning electron microscopy Chemistry Transmission electron microscopy Carbon nanotubes Biomarkers Cancer detection Biochemistry Dentistry Immune system
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

A Study of Single-Walled Carbon Nanotube Cap Structure Using Field Emission Image

Individual single-walled carbon nanotubes with vertical alignment

Visualization of single-wall carbon nanotube (SWNT) networks in conductive polystyrene nanocomposites by charge contrast imaging.

An amperometric immunosensor based on carbon nanotube embedded conducting polymer

Hot-wire chemical vapor deposition of carbon nanotubes

Deposition of Various Metals on Vertically-Aligned Single-Walled Carbon Nanotubes

In-situ transmission electron microscopy studies of polymer-carbon nanotube composite deformation.

Electrochemical immunosensor for CD8+ T-cells based on a functionalized multi-walled carbon nanotubes-modified electrode

Scanning Probe Microscopy of Carbon Nanotube Electronic Devices

Single-walled carbon-nanotube forest immunosensor for amplified detection of cancer biomarkers

Similar Documents

A Study of Single-Walled Carbon Nanotube Cap Structure Using Field Emission Image

Individual single-walled carbon nanotubes with vertical alignment

Visualization of single-wall carbon nanotube (SWNT) networks in conductive polystyrene nanocomposites by charge contrast imaging.

An amperometric immunosensor based on carbon nanotube embedded conducting polymer

Hot-wire chemical vapor deposition of carbon nanotubes

Deposition of Various Metals on Vertically-Aligned Single-Walled Carbon Nanotubes

In-situ transmission electron microscopy studies of polymer-carbon nanotube composite deformation.

Electrochemical immunosensor for CD8+ T-cells based on a functionalized multi-walled carbon nanotubes-modified electrode

Scanning Probe Microscopy of Carbon Nanotube Electronic Devices

Single-walled carbon-nanotube forest immunosensor for amplified detection of cancer biomarkers