NDLI: An Abnormal EEG Simulation Based on The Chay Model of An Excitable Neuron

Content Provider	IEEE Xplore Digital Library
Author	Manling Ge Guoya Dong Hui Meng Lei Wang Shuo Yang Baozhu Wang CuiPing Zhao
Copyright Year	2005
Description	Author affiliation: Province-Min. Joint Key Lab. of Electromagn. Field & Electr. Apparatus Reliability, Hebei Inst. of Technol., Tianjin (Manling Ge; Guoya Dong; Hui Meng; Lei Wang; Shuo Yang; Baozhu Wang; CuiPing Zhao)
Abstract	The work here presents an abnormal EEC simulation by using the electrophysiological model of the neuron. The spike wave and the multi-spike wave of the EEG morphology are reconstructed. The simulation model is derived from the Chay model, which describes the abnormal process in an excitable neuron via bifurcation. The abnormal process, that spiking can be transformed into bursting rapidly, can be observed in some disorder of the nerve system, such as epileptic seizure. The spike wave is simulated by step changes in the bifurcation parameter, which is proportion to the concentration of the intracellular calcium ions $(\|Ca\|_{1}$ ). And, when the concentration of (\|Ca\|1 is sufficiently large, the multi-spike wave can also be reconstructed. The simulation work will be helpful to understand how the EEG morphology is formed from the microcosmic viewpoint
Starting Page	45
Ending Page	47
File Size	1908112
Page Count	3
File Format	PDF
ISBN	0780387104
DOI	10.1109/CNE.2005.1419547
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2005-03-16
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Couplings Resistors Neurons Epilepsy Bifurcation Electrocardiography Electrophysiology Brain modeling Electroencephalography Oscillators
Content Type	Text
Resource Type	Article

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