NDLI: Isolation of collagen type II from bovine tracheal cartilage

Content Provider	IEEE Xplore Digital Library
Author	Soto-Herrera, M.E. Casadiegos, S.A. Fontanilla, M.R.
Copyright Year	2013
Description	Author affiliation: Grupo de Trabajo en Ing. de Tejidos, Univ. Nac. de Colombia, Manizales, Colombia (Soto-Herrera, M.E.; Casadiegos, S.A.; Fontanilla, M.R.)
Abstract	Currently, the treatment of articular cartilage defects results in tissue repair that leads to osteoarthritis [1]. Autologous chondrocyte implantation (ACI) is a technique based in obtaining autogenous chondrocytes from a cartilage biopsy. After culturing, the cells are seeded onto biodegradable scaffolds that provide the environment required for growing them. The grown chondrocytes replace and remodel the scaffold to produce artificial cartilage used for grafting. Indeed, surgical procedures based on artificial tissue have been already marketed in USA and Europe $(Carticel^{®},$ BioCart). Unfortunately, the clinical implementation of ACI has been limited by its high cost: Colombian patients who need ACI must travel to USA, Italy or Israel where authorized cell processing facilities are located. Therefore, there is a need for the development of in-site production of tissue engineered cartilage to provide patients of all socioeconomic status with ACI at a reasonable cost. A commonly biomaterial used to manufacture scaffolds for engineering artificial cartilage is collagen type II, a major component of the cartilage extracellular matrix. In this work scaffolds were produced using pure collagen type II isolated from bovine trachea. The microstructure of them was also studied.
Starting Page	1
Ending Page	1
File Size	154584
Page Count	1
File Format	PDF
ISBN	9781467362542
ISSN	2327817X
e-ISBN	9781467362573
DOI	10.1109/PAHCE.2013.6568331
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-04-29
Publisher Place	Colombia
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	tissue engineering regeneration engineering Bovine Conferences Maintenance engineering Arthritis Electronic mail biomembranes Couplings biodegradable materials proteins biomedical materials Osteoarthritis
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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