NDLI: Study on the Influenza AVirus H5N1 Based on the Z-Curve Method

Content Provider	IEEE Xplore Digital Library
Author	Yan-ling Yang
Copyright Year	2008
Description	Author affiliation: Key Lab. of Biophys., Universities of Shandong, De Zhou (Yan-ling Yang)
Abstract	All over the world, many countries and regions have been made suffer a lot by the Avian Influenza. Especially Influenza A virus H5N1, which can cause illness in humans and many other animal species, has been a focus on many scientists. So it has become more and more important to research the evolution of the H5N1 and its features. There are many approaches to study the Influenza A virus H5N1. Among these methods the Z curve is a very useful method for visualizing and analyzing DNA sequences. It is a three-dimensional space curve constituting the unique representation of a given DNA sequence in the sense that each can be uniquely reconstructed from the other. This paper picks up the some DNA sequences of the Influenza A virus H5N1 (HA) from the NCBI database , which root in the same kind of host--chicken but occurred in different countries and different years, 2006,2007 and 2008, respectively. Based on the Z-Curve theory, we map the relevant curves and compare them, then calculate the base content. The conclusion is the corresponding Z curves of the sequences have some special geometrical features. It shows that the aberrance or evolution of Influenza A virus H5N1 (HA) relates with areas and years.
Sponsorship	Eng. Technol. Press, Hong Kong
Starting Page	365
Ending Page	368
File Size	369822
Page Count	4
File Format	PDF
ISBN	9780769535616
DOI	10.1109/FBIE.2008.26
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-12-18
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Sequences Genetic mutations Influenza Humans DNA Production Educational institutions Capacitive sensors Vaccines Diseases
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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