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Diagnostic use of the resistive device in COPD patients

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2010 IEEE Region 8 International Conference on Computational Technologies in Electrical and Electronics Engineering (SIBIRCON)

2008 IEEE Region 8 International Conference on Computational Technologies in Electrical and Electronics Engineering

Diagnostic use of the resistive device in COPD patients

Content Provider	IEEE Xplore Digital Library
Author	Grishin, O.V. Gultyaeva, V.V. Uryumtsev, D.Y. Zinchenko, M.I. Grishin, V.G.
Copyright Year	2015
Description	Author affiliation: Design Technol. Inst. of Digital Tech. Novosibirsk, Novosibirsk, Russia (Grishin, V.G.) \|\| Res. Inst. of Physiol. & Basic Med., Fed. State Budgetary Sci. Instn. Sci., Novosibirsk, Russia (Grishin, O.V.; Gultyaeva, V.V.; Uryumtsev, D.Y.; Zinchenko, M.I.)
Abstract	INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is diagnosed in later or very advanced stages. The aim of the study was to evaluate feasibility of low respiratory resistive load (LRRL) in patients with COPD for a new objective method of early COPD diagnostics and to examine changes in pulmonary gas exchange during LRRL. METHODS: The study involved eleven patients with mild or moderate COPD and fourteen healthy adult volunteers. After anthropometric and spirometric measuring, pulmonary gas exchange was measured for 7 minutes using the breath-by-breath method under two conditions: 1) without respiratory resistive load (WRL); 2) with LRRL 0.4 cm $H_{2}O$ · $l^{-1}$ · s. Valve system (Intersurgical, UK) was used as a resistive device. RESULTS: Decrease in oxygen consumption $(VO_{2})$ and carbon dioxide production $(VCO_{2})$ during LRRL was significantly greater in COPD patients than in healthy subjects (14 vs. 8 %, p<;0.009 and 16 vs. 10 %, p<;0.020 respectively). In contrast, tidal volume increased by 13 % in healthy subjects only. CONCLUSION: Pulmonary gas exchange shift during low respiratory resistive load appears to be a feasible criterion of early COPD diagnostics. Future research is needed to examine sensitivity and specificity of the method.
Starting Page	146
Ending Page	149
File Size	140983
Page Count	4
File Format	PDF
ISBN	9781467391092
e-ISBN	9781467391115
DOI	10.1109/SIBIRCON.2015.7361871
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-10-28
Publisher Place	Russia
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Water Heart rate respiratory resistive load Carbon dioxide pulmonary gas exchange Valves Diseases Immune system resistive device chronic obstructive pulmonary disease
Content Type	Text
Resource Type	Article

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