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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Chun-Wu Chen Roehm, U. |
| Copyright Year | 2005 |
| Description | Author affiliation: University of Sydney (Chun-Wu Chen) |
| Abstract | We investigate how clusters and grid computing can be combined with a service-oriented architecture. An important application is the parallelization of dataintensive algorithms as they are common in life sciences, such as the sequence alignment problem. We developed a prototype of a service-oriented parallel Basic Local Alignment Search Tool (BLAST) [1]. Using a standard grid middleware, the Globus Toolkit [19], we have distributed data and logic over several cluster nodes, all of which have access to a shared database. This allows us to parallelize BLAST by combining both functional and domain decomposition. In an experimental performance evaluation, we investigate the scalability and performance of the developed BLAST service. Our results show that dataintensive algorithms can be effectively parallelized using a service-oriented approach, offering linear scalability. At the same time, our approach facilitates the sharing of functionality through a programmatic interface and further offers plug-and-play extensibility. |
| Starting Page | 1154 |
| Ending Page | 1154 |
| File Size | 369609 |
| Page Count | 1 |
| File Format | |
| ISBN | 0769526578 |
| DOI | 10.1109/ICDE.2005.171 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2005-04-03 |
| Publisher Place | Japan |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Scalability Clustering algorithms Prototypes Computer architecture Grid computing Computer networks Australia Middleware Bioinformatics Distributed computing |
| Content Type | Text |
| Resource Type | Article |
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