NDLI: GATE Simulation of a BGO Based High Sensitivity Small Animal PET Scanner

Content Provider	IEEE Xplore Digital Library
Author	Qinan Bao Chatziioannou, A.F.
Copyright Year	2007
Description	Author affiliation: UCLA, Los Angeles (Qinan Bao; Chatziioannou, A.F.)
Abstract	A BGO based small animal PET scanner dedicated for imaging small rodent was simulated by GATE. The virtual PET scanner had the same ring diameter, axial field of view (FOV) and crystal arrangement as the LSO based Siemens Inveon PET system, but was simulated with varied crystal lengths. The simulated system sensitivity was 11.6%, 19.3% and 25.5% for 10, 15 and 20 mm BGO at an energy window of 250-750 keV. The spatial resolution was measured at radial offsets of 0, 15 and 28 mm from the center of the FOV for the three crystal thicknesses. The FWHM in the radial and tangential directions was below 2.5 mm and 1.8 mm respectively for all three crystal thicknesses, up to a 30 mm diameter FOV. Scatter fraction and count rate performance were measured using a line source inserted in a water cylinder 70 mm long and 25 mm diameter for the 20 mm BGO system. The maximum NECR was 0.99 Mcps at 24 MBq and the phantom scatter fraction was 4.5% with an energy window of 250-750 keV and a timing window of 12 ns. The BGO based PET scanner was compared with the Inveon and the microPET Focus 220 systems. With the same crystal thickness, the BGO scanner had higher system sensitivity than the LSO and further improvement in sensitivity can be achieved by using thicker crystals without sacrificing much spatial resolution. Both radial and tangential resolutions were comparable to the LSO based systems. At the evaluated energy window of 250-750 keV, the phantom scatter fraction was similar to the Inveon system, while the crystal scatter fraction was about 10% lower. The maximum NECR was lower than Inveon and was achieved at a lower activity level. Simulation of the BGO PET scanner proved the design concept of a high sensitivity small animal PET scanner, with comparable spatial resolution, similar phantom scatter fraction, and acceptable count rate performance.
Starting Page	47
Ending Page	50
File Size	223247
Page Count	4
File Format	PDF
ISBN	9781424409488
DOI	10.1109/NFSI-ICFBI.2007.4387684
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2007-10-12
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Animals Scattering Rodents Focusing Imaging phantoms Timing Positron emission tomography Spatial resolution Water resources Thickness measurement
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in