NDLI: The Inverse Protein Folding Process by Artificial Life Approaches

Content Provider	IEEE Xplore Digital Library
Author	WeiXin Kang Jing Zhang MaoZu Guo Wei Peng
Copyright Year	2008
Description	Author affiliation: Coll. of Comput. Sci. & Technol., Harbin Eng. Univ., Harbin (WeiXin Kang; Jing Zhang)
Abstract	We discuss general implications of artificial life approaches to protein folding which makes an attempt at simulating the actual folding process rather than just trying to predict its final result. A new inverse folding method is presented that tries to determine the unknown proteins from tertiary structure to protein sequence by model the folding process. The method of protein inverse folding is based on 3D off lattice model with united atom. The folding process model and discovery of protein folding pathway is discussed by three artificial life approaches from protein tertiary to series of residues. The comparison and relation of the three artificial life approaches are also analyzed and it is found out: the inverse folding method is absolutely new method, and it is viable and excited.
Starting Page	35
Ending Page	38
File Size	260150
Page Count	4
File Format	PDF
ISBN	9780769531120
DOI	10.1109/ICICSE.2008.64
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-01-28
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Computer science Protein engineering Computational modeling Computer simulation Lattices Predictive models Educational institutions Amino acids Protein sequence Internet
Content Type	Text
Resource Type	Article

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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