NDLI: Quantifying stage progress of cirrhotic livers based on statistic shape models

Content Provider	IEEE Xplore Digital Library
Author	Yen-Wei Chen Chunhua Dong Xian-Hua Han Tateyama, T. Kanasaki, S. Furukawa, A.
Copyright Year	2013
Description	Author affiliation: Tokyo Metropolitan Univ., Hachioji, Japan (Furukawa, A.) \|\| Koseikai Takeda Hosp., Kyoto, Japan (Kanasaki, S.) \|\| Coll. of Inf. Sci. & Eng., Ritsumeikan Univ., Kusatsu, Japan (Yen-Wei Chen; Chunhua Dong; Xian-Hua Han; Tateyama, T.)
Abstract	It is widely known that morphological changes of the liver and the spleen occur during the clinical course of chronic liver diseases. In this paper, we show a preliminary study on quantifying stage progress of cirrhotic liver based on statistical shape models (SSMs). We constructed not only the liver SSM, but also the spleen SSM and a joint SSM of the liver and the spleen for a morphologic analysis of the cirrhotic liver in CT images. The effective modes are selected based on both its accumulation contribution rate and its correlation with doctor's opinions (stage labels). Both normal and abnormal livers including temporal sequence data are projected to the subspace with the selected modes. Most of the normal data are located in the center, while abnormal data are scattered around the normal data. If the disease progresses, data will move outside. The distance to the center can be used to quantify the stage progress of the cirrhotic liver.
Sponsorship	IEEE Eng. Med. Biol. Soc.
Starting Page	822
Ending Page	825
File Size	419278
Page Count	4
File Format	PDF
e-ISBN	9781479927616
DOI	10.1109/BMEI.2013.6747054
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-12-16
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Shape Liver diseases Computational modeling Mode selection Morphologic change Educational institutions CT Volume Statistical shape model Computed tomography Stage progress Cirrhotic liver Joints Principal component analysis
Content Type	Text
Resource Type	Article

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