NDLI: The effect of mechanical strain on proliferation of lung cancer A549 cells and Squamous Carcinoma of Tongue Tca8113 Cells

Content Provider	IEEE Xplore Digital Library
Author	Hua Qu Peng Gao
Copyright Year	2011
Description	Author affiliation: College of Science, Tianjin Polytechnic University, Tianjin, China (Hua Qu) \|\| Institute of Applied Mechanics and Biomedical Engineering, Taiyuan University of Technology, Taiyuan, China (Peng Gao)
Abstract	Using FX-4000 strain unit, the proliferation of human lung adenocarcinoma A549 cells and Squamous Carcinoma of Tongue Tca8113 Cells that underwent different mechanical strain were studied. Flow Cytometer was adopted to investigate the proliferation of A549 cells and Tca8113 cells. Experimental results indicated that cell proliferation index (PI) reduced significantly after A549 cells and Tca8113 cells were subjected to square wave with 15% elongation at frequency 0.5Hz for 4h, the PI had no distinct difference for sine wave and triangle wave treated A549 cells and Tca8113 cells when compared with the control group. It was indicated that cyclic stretch could inhibit the proliferation of A549 cells and Tca8113 cells, the waveform play important roles in inhibiting proliferation.
Starting Page	1533
Ending Page	1536
File Size	269101
Page Count	4
File Format	PDF
ISBN	9781424493517
e-ISBN	9781424493524
DOI	10.1109/BMEI.2011.6098510
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-10-15
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Tongue Lungs proliferation Humans Cells (biology) lung adenocarcinoma A549 cells Indexes cyclic stretch Squamous Carcinoma of Tongue Cells waveform Strain Cancer
Content Type	Text
Resource Type	Article

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