NDLI: SmartWarf - A portable automated warfarin dosing tool

Content Provider	IEEE Xplore Digital Library
Author	Zhongming Zhao Kansal, S. Bukaveckas, B.L.
Copyright Year	2009
Description	Author affiliation: Department of Psychiatry, Center for the Study of Biological Complexity, Department of Human and Molecular Genetics, Department of Pharmacy, Department of Bioinformatics, and Department of Pathology, Virginia Commonwealth University, Richmond, USA (Zhongming Zhao; Kansal, S.; Bukaveckas, B.L.)
Abstract	Warfarin is the most frequently prescribed oral anticoagulant and the second most common drug implicated in emergency room visits for adverse drug events. At present, the appropriate dose of warfarin is usually determined empirically on an individual basis by measuring patient response, which has up to 60-fold variation among individuals. It is now understood that patient demographics and genetic variability result in significant differences in warfarin doses required for effective and safe treatment. To help the clinician to calculate a patient-specific dose in real time based on the clinical and genotyping data, we developed SmartWarf, a user-friendly portable tool to help individualize warfarin dosing and follow-up. SmartWarf works in a personal digital assistant (PDA) or desktop computer and allows for the clinician to input and update the clinical data and results of the genetic tests. SmartWarf applies a dosing algorithm to calculate the dose and dose interval for the patient. Actual dosing prescribed and follow-up warfarin care are inputted into the PDA which is synchronized with either a hospital/physician office SmartWarf database or with a national core SmartWarf database. In the server environment, a centralized database stores the predicted and actual warfarin doses as well as patient's de-identified clinical and genetic data. The SmartWarf technology provides a real time and portable medical data transmission and handling tool.
Starting Page	348
Ending Page	355
File Size	406991
Page Count	8
File Format	PDF
ISBN	9781424445844
DOI	10.1109/CTS.2009.5067500
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-05-18
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Drugs Warfarin Medical treatment Genomics SmartWarf Personalized Medicine PDA Databases Computer errors Genetics Medical Data Transmission Data communication Personal digital assistants Bioinformatics Real Time Dosing Testing
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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