NDLI: Interference microscopy volume illustration for biomedical data

Content Provider	IEEE Xplore Digital Library
Author	Hanqi Guo Xiaoru Yuan Jie Liu Guihua Shan Xuebin Chi Fei Sun
Copyright Year	2012
Description	Author affiliation: Key Laboratory of Machine Perception (Ministry of Education), and School of EECS, Peking University, China (Hanqi Guo; Xiaoru Yuan; Jie Liu) \|\| Computer Network Information Center, Chinese Academy of Sciences, China (Fei Sun)
Abstract	In this paper, we propose a novel volume illustration technique inspired by interference microscopy, which has been successfully used in biological, medical and material science over decades. Our approach simulates the optical phenomenon in interference microscopy that accounts light interference over transparent specimens, in order to generate contrast enhanced and illustrative volume visualization results. Specifically, we propose PCVR (Phase- Contrast Volume Rendering) and DICVR (Differential Interference Contrast Volume Rendering) corresponding to Phase-Contrast microscopy and Differential Interference Contrast (DIC) microscopy respectively. Without complex transfer function design, our proposed method can enhance the image contrast and structure details according to the subtle change of Optical Path Differences (OPD), and illustrate the thickness change and occluded structures with interferometry metaphors. In addition, we also develop a user interface to enable slicing specimen sections in volume data. Focus+ context lens are also included in the system for convenient data navigation and exploration. As the proposed methods are based upon widely applied microscopy techniques, they are intuitive for domain experts to explore and analyze the volume data with the proposed methods. The feedbacks from domain users suggest our proposed techniques are useful volume visualization approaches complimentary to the traditional ones.
Starting Page	177
Ending Page	184
File Size	27918243
Page Count	8
File Format	PDF
ISBN	9781467308632
ISSN	21658773
e-ISBN	9781467308663
e-ISBN	9781467308656
DOI	10.1109/PacificVis.2012.6183589
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-02-28
Publisher Place	Korea (South)
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Optical microscopy feature enhancement volume rendering Microscopy Data visualization interference microscopy Interference Rendering (computer graphics) Optical imaging Optical refraction biomedical visualization Volume illustration
Content Type	Text
Resource Type	Article

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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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