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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | AnGuo Dong Lin Gao XiaoFeng Zhou HongYu Su |
| Copyright Year | 2007 |
| Description | Author affiliation: Xidian Univ., Xi'an (AnGuo Dong; Lin Gao; XiaoFeng Zhou; HongYu Su) |
| Abstract | When referred to functional motif discovery in biological network and drug target recognition in pharmaceutical chemistry, the most important step is to mine subgraphs with certain structure in a graph. Fortunately we notice that those kinds of subgraphs are frequently characterized by a Hamiltonian cycle. Hence, in this paper we develop a matrix theory based approach for mining such subgraphs. Firstly we study the properties of Hamiltonian subgraphs and determine the k-path based on the properties to find subgraph with Hamiltonian cycle. Then, an algorithm for mining subgraph with Hamiltonian cycle is designed under the frame of this approach. Finally, we analyze the complexity of the algorithm and simulate it on five real networks to verify our algorithms. The simulation results show that our algorithms have high efficiency. |
| Starting Page | 288 |
| Ending Page | 292 |
| File Size | 296382 |
| Page Count | 5 |
| File Format | |
| ISBN | 9780769528748 |
| DOI | 10.1109/FSKD.2007.138 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2007-08-24 |
| Publisher Place | China |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Algorithm design and analysis Computer science Drugs Algebra Pharmaceutical technology Target recognition Heuristic algorithms Biology Data mining Chemical technology |
| Content Type | Text |
| Resource Type | Article |
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