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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Hyung Jung Yoo Sangmin Lee Jaehyun Ahn Sungjin Oh Byeonghwa Song Sung Jae Kim Jong-Mo Seo Tae-You Kim Dong-il Cho |
| Copyright Year | 2013 |
| Description | Author affiliation: Dept. of Electr. Eng. & Comput. Sci., Seoul Nat. Univ., Seoul, South Korea (Jong-Mo Seo) || ASRI, Seoul Nat. Univ., Seoul, South Korea (Hyung Jung Yoo; Sangmin Lee; Jaehyun Ahn; Sungjin Oh; Byeonghwa Song; Dong-il Cho) || Cancer Res. Inst., Seoul Nat. Univ., Seoul, South Korea (Tae-You Kim) || ISRC, Seoul Nat. Univ., Seoul, South Korea (Sung Jae Kim) |
| Abstract | Bacteria-based biomedical microrobots have been proposed to achieve effective localized drug delivery. To enhance a directional locomotion of bacteria-attached microsystem, structures with selective bacterial adhesion are necessary. Having different surface morphologies of microstructures is beneficial for selective attachments of bacteria. In this paper, a surface energy modification method for controlling bacterial adhesion on biodegradable-polymer structures is presented. This is achieved by controlling exposed doses of x-ray synchrotron irradiation. To calculate the x-ray exposure time for varying the surface morphology of the biodegradable polymeric devices, the equation for exposed dose is derived. The contact angles of different surfaces are measured, and the corresponding surface energies are calculated to verify the modification of the surface morphology. As a result, the surface energy increases with the increment of the exposed dose to the biodegradable-polymer. The developed surface energy modification method is suitable for modifying the polymeric surface without additional physical/chemical treatments. The fabricated cubic structures with different surface morphologies can be used for effectively flagellating bacteria on selective surfaces for directional locomotion. |
| Sponsorship | IEEE Ind. Electron. Soc. |
| Starting Page | 1521 |
| Ending Page | 1524 |
| File Size | 1198042 |
| Page Count | 4 |
| File Format | |
| ISBN | 9788993215052 |
| ISSN | 20937121 |
| DOI | 10.1109/ICCAS.2013.6704128 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2013-10-20 |
| Publisher Place | South Korea |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Selective bacterial adhesion Microorganisms Adhesives Surface energy modification Films Surface morphology X-ray synchrotron irradiation Biodegradable-polymer Polymers Drug delivery system Biomedical imaging Photonics |
| Content Type | Text |
| Resource Type | Article |
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