NDLI: A computer simulation study of cell seeding of a porous biomaterial

Content Provider	IEEE Xplore Digital Library
Author	Robu, A.P. Neagu, A. Stoicu-Tivadar, L.
Copyright Year	2010
Description	Author affiliation: Department of Automation and Applied Informatics ¿Politehnica¿ University of Timisoara, Bd. Vasile Parvan no. 2, 300223 Timisoara, Romania (Robu, A.P.; Stoicu-Tivadar, L.) \|\| Center for Modeling Biological Systems and Data Analysis, Department of Biophysics and Medical Informatics, Victor Babes University of Medicine and Farmacy Timisoara, Bd. Eftimie Murgu no. 2, 300041 Timisoara, Romania (Neagu, A.)
Abstract	Tissue engineering is a part of regenerative medicine that handles in vitro creation of biological tissue substitutes which may repair or substitute injured or diseased parts of the body. In order to create tissue structures, biocompatible materials with a porous structure (scaffolds) are used as support for cells. The paper presents the stages of development and the software application that results, used as support for the study of cell seeding of a three-dimensional scaffold. The application uses an algorithm based on the Metropolis Monte Carlo method. The program was developed by using the Visual Basic.Net programming environment. Ideally, cell seeding should be fast and should achieve an uniform distribution of the cell population in the scaffold. In a first stage, the program creates the initial configuration of the system consisting of a cell suspension placed in the neighborhood of a scaffold immersed in cell culture medium. Starting from this configuration, using our software application the movement of the cells in suspension is studied as well as their potential of getting attached to the biomaterial.
Starting Page	225
Ending Page	229
File Size	626986
Page Count	5
File Format	PDF
ISBN	9781424474325
e-ISBN	9781424474332
DOI	10.1109/ICCCYB.2010.5491294
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-05-27
Publisher Place	Romania
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Biomedical materials Computer simulation Regeneration engineering Tissue engineering Biological tissues Potential well Application software In vitro Biological materials Programming environments
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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