NDLI: 3D simulations of difference frequency effects on a blood vessel in ultrasound-stimulated vibro-acoustography

Content Provider	IEEE Xplore Digital Library
Author	Heikkila, J. Karjalainien, T. Vauhkonen, M. Hynynen, K.
Copyright Year	2005
Description	Author affiliation: Dept. of Appl. Phys., Kuopio Univ., Finland (Heikkila, J.; Karjalainien, T.; Vauhkonen, M.)
Abstract	Ultrasound-stimulated vibro-acoustography (USVA) is one of the recent noninvasive techniques that have been developed to explore mechanical properties of soft tissues. USVA is based on the interference of two focused ultrasound beams that have a slightly different frequency. This interference produces time variation to the acoustic radiation force that vibrates the joint focal region at the difference frequency. In this paper, we have simulated displacement amplitudes in the blood vessel using different difference frequencies and elasticity parameters. The difference frequency was varied between 300 Hz and 2.5 kHz, and two different stiffness parameters (60 kPa and 120 kPa) for the blood vessel wall were used. The stimulation transducer used in the simulations consists of two concentric and focused ring elements whose base frequency is 0.75 MHz. The stimulation fields have been computed in a homogeneous domain using the Rayleigh integral. The simulations of the vibrations have been computed using the finite element method. The displacement simulations are computed in an inhomogeneous domain that consists of soft tissue and a blood vessel. From the simulations, it can be seen that USVA is sensitive to the mechanical properties of vessel wall and that the displacements are highly dependent on the difference frequency and the material parameters.
Starting Page	1247
Ending Page	1250
File Size	729785
Page Count	4
File Format	PDF
ISBN	0780384121
ISSN	10510117
DOI	10.1109/ULTSYM.2004.1418014
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2004-08-23
Publisher Place	Canada
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Frequency Blood vessels Ultrasonic imaging Computational modeling Mechanical factors Biological tissues Interference Noninvasive treatment Acoustic beams Elasticity
Content Type	Text
Resource Type	Article

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