NDLI: Analyte detection using an ion-channel sensor array

Content Provider	IEEE Xplore Digital Library
Author	Sattigeri, P.S. Ramamurthy, K.N. Thiagarajan, J.J. Goryll, M. Spanias, A. Thornton, T.
Copyright Year	2011
Description	Author affiliation: SenSIP and CSSER Center, School of ECEE, Arizona State University, Tempe, USA (Sattigeri, P.S.; Ramamurthy, K.N.; Thiagarajan, J.J.; Goryll, M.; Spanias, A.; Thornton, T.)
Abstract	Ion-channel sensors can be used for detecting small metal ions and organic molecules. The sensor consists of a chamber with a lipid bilayer hosting ion channels produced by protein insertion. These channels allow selective transport and produce a characteristic signal across the chamber for each analyte. A four chamber ion channel sensor array is built for accurate analyte detection. In this paper, we address the case in which non-uniform number of channels formed in each chamber. The power distribution information in the transform domain is used as features for each chamber signal. We employ support vector regression to estimate the number of channels inserted in each chamber and normalize the chamber signal features. The change observed in the normalized features of the chamber containing the analyte with respect to other chambers is used for detection. Results show high accuracy rates for detection of analyte using simulated data and experimental data.
Starting Page	1
Ending Page	6
File Size	426956
Page Count	6
File Format	PDF
ISBN	9781457702730
e-ISBN	9781457702747
DOI	10.1109/ICDSP.2011.6004913
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-07-06
Publisher Place	Greece
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Channel estimation Lipidomics Markov processes Switches Analytical models Kernel Feature extraction Support Vector Regression Ion-channel Wavelet kernel
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in