NDLI: Modelling of contrast enhancement for cardiac multi-detector row CT

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Modelling of contrast enhancement for cardiac multi-detector row CT

Motion estimation with candidate block and pixel subsampling algorithm

2004 IEEE International Workshop on Imaging Systems and Techniques (IST) (IEEE Cat. No.04EX896)

Modelling of contrast enhancement for cardiac multi-detector row CT

Content Provider	IEEE Xplore Digital Library
Author	Numburi, U. Chatzimavroudis, G.P. Uber, A.E. Kalafut, J.P. Stillman, A.E. White, R.D. Halliburton, S.S.
Copyright Year	2005
Description	Author affiliation: Dept. of Chem. & Biomed. Eng., Cleveland State Univ., OH, USA (Numburi, U.; Chatzimavroudis, G.P.)
Abstract	Cardiac computed tomography (CT) requires intravascular injection of iodinated contrast agent to visualize the cardiac chambers, large vessels, and coronary arteries. Currently, the standard injection protocol used clinically is uniphasic (fixed volume of contrast agent injected at a single flow rate). This results in non-uniform enhancement of the blood pool in some patients. The purpose of this work was to develop an algorithm for determining patient-specific contrast injection protocols necessary to consistently achieve optimal uniform enhancement in the left heart on multi-detector row CT (MDCT) images. A model was developed using the patient-function approach: the injection administered to the patient was the input and the corresponding enhancement observed in the region-of-interest was the output of the system. These input and output functions were related via the transfer-function which was computed in the Fourier domain. The model was first validated clinically using standard uniphasic contrast injection protocols. Then, the model was implemented to determine the patient-specific injection protocol necessary to achieve the desired enhancement in the left heart. The resulting enhancement in the diagnostic images was in agreement with the desired enhancement. The results indicate that it is possible to determine a patient-specific injection protocol in order to achieve uniform enhancement in MDCT images of the left heart.
Starting Page	125
Ending Page	129
File Size	284124
Page Count	5
File Format	PDF
ISBN	0780389220
DOI	10.1109/IST.2005.1594543
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2005-05-13
Publisher Place	Canada
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Protocols Computed tomography Heart Blood Anatomy Static VAr compensators Chemical engineering Biomedical engineering Radiology Visualization
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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